Morphological imaging of gastrointestinal and lung neuroendocrine neoplasms

نویسندگان

چکیده

Neuroendocrine neoplasms (NENs) predominantly arise within the intestinal tract, pancreas, and lung, but may develop in various organs commonly metastasize, especially to liver. Cross-sectional imaging (ultrasound, computed tomography, magnetic resonance imaging) play a central role detection, characterization, management, follow-up of NENs. Imaging features tumors significantly vary as per site primary tumor, tumor grade, differentiation. Most low-grade NEN present slow-growing well-delineated solid enhancing tumors, while higher-grade are typically larger, more heterogeneous masses with inner necrosis, calcification, frequent locoregional distant spread. This short review article aims main lung gastroenteropancreatic NENs on morphological techniques discuss their performance. liver metastases will not be precisely detailed.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Histopathology of gastrointestinal neuroendocrine neoplasms

Gastrointestinal neuroendocrine neoplasms (GI-NENs) arise from neuroendocrine cells distributed mainly in the mucosa and submucosa of the gastrointestinal tract. In 2010, the World Health Organization (WHO) classification of NENs of the digestive system was changed, categorizing these tumors as grade 1 neuroendocrine tumor (NET), grade-2NET, neuroendocrine carcinoma (large- or small-cell type),...

متن کامل

Neuroendocrine neoplasms of the gastrointestinal tract.

BACKGROUND Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are complex tumors whose incidence is rising and whose treatment requires precise classification and risk stratification. METHOD Selective review of the relevant literature, including recently published guidelines. RESULTS GEP-NENs are initially classified by their degree of histological differentiation and their graded c...

متن کامل

Diagnosis and therapy of neuroendocrine neoplasms of the gastrointestinal tract

A neuroendocrine neoplasm (nen) is a tumor that originates in neuroendocrine cells capable of producing peptides or amines. neuroendocrine neoplasms of the digestive system are also referred to as gastroenteropancreatic neuroendocrine neoplasms (GeP nen) and constitute a heterogeneous group of growths originating from at least 15 types of specialized cells spread throughout the stomach, small i...

متن کامل

Morphological and immunohistochemical profile of pancreatic neuroendocrine neoplasms.

The study represents a comprehensive retrospective morphological and immunohistochemical profiling of pancreatic neuroendocrine neoplasms (PNENs) in order to reveal the associations between morphological and molecular parameters. The local tumour spread (T), presence of metastases in regional lymph nodes (N) and distant organs (M), tumour grade (G) and resection line status (R) by pathology fin...

متن کامل

Endoscopic Biopsy in Gastrointestinal Neuroendocrine Neoplasms: A Retrospective Study

BACKGROUND Gastrointestinal neuroendocrine neoplasms (GI-NENs) are often located in the deep mucosa or submucosa, and the efficacy of endoscopic biopsy for diagnosis and treatment of GI-NENs is not fully understood. OBJECTIVE The current study analyzed GI-NENs, especially those diagnosed pathologically and resected endoscopically, and focused on the biopsy and cold biopsy forceps polypectomy ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Current Opinion in Endocrine and Metabolic Research

سال: 2021

ISSN: ['2451-9650']

DOI: https://doi.org/10.1016/j.coemr.2021.05.001